HT-001

WHAT IS HT-001?

HT-001 is a topical formulation under development for the treatment of patients mild to moderate rash and skin disorders associated with initial and repeat courses of tyrosine kinase inhibitor/epidermal growth factor receptor (EGFR) inhibitor therapy. EGFR inhibitors are used for treatment of cancers with EGFR up-regulation (such as non-small cell lung cancer, pancreatic cancer, breast cancer, and colon cancer). However, EGFR inhibitors are often associated with dose-limiting skin toxicities that can result in interruption of treatment. HT-001 is targeted to treat these EGFR-induced skin disorders to allow patients to achieve the best potential outcomes of EGFR therapy.

In July 2019 Hoth entered into a Sponsored Research Agreement with the George Washington University (GW) to explore preclinical pharmacology studies with topically administered HT-001.

DEVELOPMENT STATUS

HT-001 is currently in the preclinical stage of development.

Upcoming Milestones:

Hoth Therapeutics is planning to request a Pre-IND Meeting with FDA in Q4 2020.

EXTERNAL RESOURCES

INVESTOR RELATIONS

Hoth Therapeutics seeks to enhance shareholder value not only through business performance and practices, but also through responsible and effective communication with its shareholders.